Publications

Below is a list of publications and preprints from researchers that used postmortem brain tissue generously donated to Autism BrainNet.

2020 Publications

Anderson M.P., Quinton R., Kelly K., Falzon A., Halladay A., Schumann C.M., Hof P.R., Tamminga C.A., Hare C.K., Amaral D.G. Autism brainnet. Arch. Pathol. Lab. Med. 2020 Sept 22; Epub ahead of print PubMed

Cioana M., Michalski B., Fahnestock M. Insulin-like growth factor and insulin-like growth factor receptor expression in human idiopathic autism fusiform gyrus tissue. Autism Res. 2020 June 01; 13, 897-907 PubMed

Huang A.Y., Li P., Rodin R.E., Kim S.N., Dou Y., Kenny C.J., Akula S.K., Hodge R.D., Bakken T.E., Miller J.A., Lein E.S., Park P.J., Lee E.A., Walsh C.A. Parallel rna and DNA analysis after deep sequencing (PRDD-seq) reveals cell type-specific lineage patterns in human brain. Proc. Natl. Acad. Sci. U S A 2020 June 23; 117, 13886-13895 PubMed

Sciara A.N., Beasley B., Crawford J.D., Anderson E.P., Carrasco T., Zheng S., Ordway G.A., Chandley M.J. Neuroinflammatory gene expression alterations in anterior cingulate cortical white and gray matter of males with autism spectrum disorder. Autism Res. 2020 June 1; 13, 870-884 PubMed

2019 Publications

DiStasio M.M., Nagakura I., Nadler M.J., Anderson M.P. T lymphocytes and cytotoxic astrocyte blebs correlate across autism brains. Ann. Neurol. 2019 Dec 1; 86, 885-898 PubMed

Wong C.C.Y., Smith R.G., Hannon E., Ramaswami G., Parikshak N.N., Assary E., Troakes C., Poschmann J., Schalkwyk L.C., Sun W., Prabhakar S., Geschwind D.H., Mill J. Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain tissue. Hum. Mol. Genet. 2019 July 1; 28, 2201-2211 PubMed

2018 Publications

Amaral D.G., Anderson M.P., Ansorge O., Chance S., Hare C., Hof P.R., Miller M., Nagakura I., Pickett J., Schumann C., Tamminga C. Autism Brainnet: A network of postmortem brain banks established to facilitate autism research. Handb. Clin. Neurol. 2018 Jan 1; 150, 31-39 PubMed

Ariza J., Rogers H., Hashemi E., Noctor S.C., Martínez-Cerdeño V. The number of chandelier and basket cells are differentially decreased in prefrontal cortex in autism. Cereb. Cortex 2018 Feb 1; 28, 411-420 PubMed

Avino T.A., Barger N., Vargas M.V., Carlson E.L., Amaral D.G., Bauman M.D., Schumann C.M. Neuron numbers increase in the human amygdala from birth to adulthood, but not in autism. Proc. Natl. Acad. Sci. U S A 2018 April 3; 115, 3710-3715 PubMed

Filipello F., Morini R., Corradini I., Zerbi V., Canzi A., Michalski B., Erreni M., Markicevic M., Starvaggi-Cucuzza C., Otero K., Piccio L., Cignarella F., Perrucci F., Tamborini M., Genua M., Rajendran L., Menna E., Vetrano S., Fahnestock M., Paolicelli R.C., Matteoli M. The microglial innate immune receptor TREM2 is required for synapse elimination and normal brain connectivity. Immunity 2018 May 15; 48, 979-991 PubMed

Lin C.Y., Chang K.W., Lin C.Y., Wu J.Y., Coon H., Huang P.H., Ho H.N., Akbarian S., Gau S.S., Huang H.S. Allele-specific expression in a family quartet with autism reveals mono-to-biallelic switch and novel transcriptional processes of autism susceptibility genes. Sci. Rep. 2018 March 9; 8, 4277 (2018) PubMed

Parras A., Anta H., Santos-Galindo M., Swarup V., Elorza A., Nieto-Gonzalez J.L., Pico S., Hernández I.H., Díaz-Hernández J.I., Belloc E., Rodolosse A., Parikshak N.N., Peñagarikano O., Fernández-Chacón R., Irimia M., Navarro P., Geschwind D.H., Mendez R., Lucas J.J. Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing. Nature 2018 Aug 1; 560, 441-446 PubMed

Shpyleva S., Melnyk S., Pavliv O., Pogribny I., James J.S. Overexpression of LINE-1 retrotransposons in autism brain. Mol. Neurobiol. 2018 Feb 1; 55, 1740-1749 PubMed

2017 Publications

Soghomonian J.J., Zhang K., Reprakash S., Blatt G.J. Decreased parvalbumin mRNA levels in cerebellar Purkinje cells in autism. Autism Res. 2017 Nov 1; 10, 1787-1796 PubMed 

Pagan C., Goubran-Botros H., Delorme R., Benabou M., Lemière N., Murray K., Amsellem F., Callebert J., Chaste P., Jamain S., Fauchereau F., Huguet G., Maronde E., Leboyer M., Launay J., Bourgeron T. Disruption of melatonin synthesis is associated with impaired 14-3-3 and miR-451 levels in patients with autism spectrum disorders. Sci. Rep. 2017 May 18; 7, 2096 PubMed

Wegiel J., Flory M., Kaczmarski W., Brown W.T., Chadman K., Wisniewski T., Nowicki K., Kuchna I., Ma S.Y., Wegiel J. Partial agenesis and hypoplasia of the corpus callosum in idiopathic autism. J. Neuropathol. Exp. Neurol. 2017 Mar 1;76, 225-237 PubMed

Hashemi E., Ariza J., Rogers H., Noctor S.C., Martínez-Cerdeño V. The number of parvalbumin-expressing interneurons is decreased in the medial prefrontal cortex in autism. Cereb. Cortex. 2017 Mar 1; 27, 1931-1943 PubMed 

Schumann C.M., Sharp F.R., Ander B.P., Stamova B. Possible sexually dimorphic role of miRNA and other sncRNA in ASD brain. Mol. Autism. 2017 Feb 7; 8, 4 PubMed

Lee A.S., Azmitia E.C., Whitaker-Azmitia P.M. Developmental microglial priming in postmortem autism spectrum disorder temporal cortex. Brain Behav. Imm. 2017 May 1; 62, 193-202 PubMed.

Menassa D.A., Sloan C., Chance S.A. Primary olfactory cortex in autism and epilepsy: Increased glial cells in autism. Brain Pathol. 2017 Jul 1; 27, 437-448 PubMed 

Ellis S.E., Gupta S., Moes A., West A.B., Arking D.E. Exaggerated CpH methylation in the autism-affected brain. Mol. Autism. 2017 Feb 17; 8, 6 PubMed

Zhubi A., Chen Y., Guidotti A., Grayson D.R. Epigenetic regulation of RELN and GAD1 in the frontal cortex (FC) of autism spectrum disorder (ASD) subjects. Int. J. Dev. Neurosci. 2017 Nov 1; 62, 63-72 PubMed

2016 Publications

Dunaway K.W., Islam M.S., Coulson R.L., Lopez S.J., Vogel Ciernia A., Chu R.G., Yasui D.H., Pessah I.N., Lott P., Mordaunt C., Meguro-Horike M., Horike S.I., Korf I., LaSalle J.M. Cumulative impact of polychlorinated biphenyl and large chromosomal duplications on DNA methylation, chromatin, and expression of autism candidate genes. Cell Rep. 2016 Dec 13; 17, 3035-3048 PubMed

Parikshak N.N., Swarup V., Belgard T.G., Irimia M., Ramaswami G., Gandal M.J., Hartl C., Leppa V., Ubieta L.T., Huang J., Lowe J.K., Blencowe B.J., Horvath S., Geschwind D.H. Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism. Nature 2016 Dec 15; 540, 423-427 PubMed 

Karst A.T., Hutsler J.J. Two-dimensional analysis of the supragranular layers in autism spectrum disorder. Res. Autism Spectr. Disord. 2016 Dec 1; 32, 96-105 Article

Sun W., Poschmann J., Cruz-Herrera Del Rosario R., Parikshak N.N., Hajan H.S., Kumar V., Ramasamy R., Belgard T.G., Elanggovan B., Wong C.C., Mill J., Geschwind D.H., Prabhakar S. Histone acetylome-wide association study of autism spectrum disorder. Cell 2016 Nov 17; 167,1385-1397 PubMed 

García-Cabezas M.Á., John Y.J., Barbas H., Zikopoulos B. Distinction of neurons, glia and endothelial cells in the cerebral cortex: An algorithm based on cytological features. Front. Neuroanat. 2016 Nov 1; 10, 107 PubMed

Wu Y.E., Parikshak N.N., Belgard T.G., Geschwind D.H. Genome-wide, integrative analysis implicates microRNA dysregulation in autism spectrum disorder. Nat. Neurosci. 2016 Nov 1; 19, 1463-1476 PubMed

Westmark C.J., Sokol D.K., Maloney B., Lahiri D.K. Novel roles of amyloid-beta precursor protein metabolites in fragile X syndrome and autism. Mol. Psychiatry 2016 Oct 1; 21, 1333-1341 PubMed

Liu X., Han D., Somel M., Jiang X., Hu H., Guijarro P., Zhang N., Mitchell A., Halene T., Ely J.J., Sherwood C.C., Hof P.R., Qiu Z., Pääbo S., Akbarian S., Khaitovich P. Disruption of an evolutionarily novel synaptic expression pattern in autism. PLoS Biol. 2016 Sep 29; 14, e1002558 PubMed

Bakulski K.M., Halladay A., Hu V.W., Mill J., Fallin M.D. Epigenetic research in neuropsychiatric disorders: the “Tissue Issue”. Curr. Behav. Neurosci. Rep. 2016 Sep 1; 3, 264-274 PubMed

Hashemi E., Ariza J., Lechpammer M., Noctor S.C., Martínez-Cerdeño V. Abnormal white matter tracts resembling pencil fibers involving prefrontal cortex (Brodmann area 47) in autism: A case report. J. Med. Case Rep. 2016 Aug 26; 10, 237 PubMed 

Ray B., Sokol D.K., Maloney B., Lahiri D.K. Finding novel distinctions between the sAPPα-mediated anabolic biochemical pathways in autism spectrum disorder and fragile X syndrome plasma and brain tissue. Sci. Rep. 2016 May 23; 6, 26052 PubMed

Ellis S.E., Panitch R., West A.B., Arking D.E. Transcriptome analysis of cortical tissue reveals shared sets of downregulated genes in autism and schizophrenia. Transl. Psychiatry 2016 May 24; 6, e817 PubMed 

Lintas C., Sacco R., Persico A.M. Differential methylation at the RELN gene promoter in temporal cortex from autistic and typically developing post-puberal subjects. J. Neurodev. Disord. 2016 Apr 29; 8,18 PubMed 

Azmitia E.C., Saccomano Z.T., Alzoobaee M.F., Boldrini M., Whitaker-Azmitia P.M. Persistent angiogenesis in the autism brain: An immunocytochemical study of postmortem cortex, brainstem and cerebellum. J. Autism Dev. Disord. 2016 Apr 1; 46, 1307-1318 PubMed

Casanova M.F., Sokhadze E., Opris I., Wang Y., Li X. Autism spectrum disorders: Linking neuropathological findings to treatment with transcranial magnetic stimulation. Acta Paediatr. 2015 Apr 1;104, 346-355 PubMed

Werling D.M., Parikshak N.N., Geschwind D.H. Gene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders. Nat. Commun. 2016 Feb 19; 7, 10717 PubMed

Hutsler J.J., Casanova M.F. Review: Cortical construction in autism spectrum disorder: columns, connectivity and the subplate. Neuropathol. Appl. Neurobiol. 2016 Feb 1; 42, 115-134 PubMed

Zhang Y., Hodgson N.W., Trivedi M.S., Abdolmaleky H.M., Fournier M., Cuenod M., Do K.Q., Deth R.C. Decreased brain levels of vitamin B12 in aging, autism and schizophrenia. PLoS One 2016 Jan 22; 11, e0146797 PubMed

2015 Publications

Crawford J.D., Chandley M.J., Szebeni K., Szebeni A., Waters B., Ordway G.A. Elevated GFAP protein in anterior cingulate cortical white matter in males with autism spectrum disorder. Autism Res. 2015 Dec 1; 8, 649-657 PubMed

Stamova B., Ander B.P., Barger N., Sharp F.R., Schumann C.M. Specific regional and age-related small noncoding RNA expression patterns within superior temporal gyrus of typical human brains are less distinct in autism brains. J. Child Neurol. 2015 Dec 1; 30, 1930-1946 PubMed

D’Gama A.M., Pochareddy S., Li M., Jamuar S.S., Reiff R.E., Lam A.T., Sestan N., Walsh C.A. Targeted DNA sequencing from autism spectrum disorder brains implicates multiple genetic mechanisms. Neuron 2015 Dec 2; 88, 910-917 PubMed

Hampson D.R., Blatt G.J. Autism spectrum disorders and neuropathology of the cerebellum. Front. Neurosci. 2015 Nov 6; 9, 420 PubMed

Wegiel J., Flory M., Schanen N.C., Cook E.H., Nowicki K., Kuchna I., Imaki H., Ma S.Y., Wegiel J., London E., Casanova M.F., Wisniewski T., Brown W.T. Significant neuronal soma volume deficit in the limbic system in subjects with 15q11.2-q13 duplications. Acta Neuropathol. Commun. 2015 Oct 13; 3, 63 PubMed

Mor M., Nardone S., Sams D.S., Elliott E. Hypomethylation of miR-142 promoter and upregulation of microRNAs that target the oxytocin receptor gene in the autism prefrontal cortex. Mol. Autism 2015 Aug 14; 6, 46 PubMed

McKavanagh R., Buckley E., Chance S.A. Wider minicolumns in autism: A neural basis for altered processing? Brain 2015 Jul 1; 138, 2034-2045 PubMed

Ander B.P., Barger N., Stamova B., Sharp F.R., Schumann C.M. Atypical miRNA expression in temporal cortex associated with dysregulation of immune, cell cycle, and other pathways in autism spectrum disorders. Mol. Autism 2015 Jun 19; 6, 37 PubMed

Barger N., Sheley M.F., Schumann C.M. Stereological study of pyramidal neurons in the human superior temporal gyrus from childhood to adulthood. J. Comp. Neurol. 2015 May 1; 523, 1054-1072 PubMed 

Hu V.W., Sarachana T., Sherrard R.M., Kocher K.M. Investigation of sex differences in the expression of RORA and its transcriptional targets in the brain as a potential contributor to the sex bias in autism. Mol. Autism 2015 May 13; 6,7 PubMed

Kim E., Camacho J., Combs Z., Ariza J., Lechpammer M., Noctor S.C., Martínez-Cerdeño V. Preliminary findings suggest the number and volume of supragranular and infragranular pyramidal neurons are similar in the anterior superior temporal area of control subjects and subjects with autism. Neurosci. Lett. 2015 Mar 4; 589, 98-103 PubMed 

Nicolini C., Ahn Y., Michalski B., Rho J.M., Fahnestock M. Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid. Acta Neuropathol. Commun. 2015 Jan 20; 3, 3 PubMed 

2014 Publications

Gupta S., Ellis S.E., Ashar F.N., Moes A., Bader J.S., Zhan J., West A.B., Arking D.E. Transcriptome analysis reveals dysregulation of innate immune response genes and neuronal activity-dependent genes in autism. Nat. Commun. 2014 Dec 10; 5, 5748 PubMed

Irimia M., Weatheritt R.J., Ellis J.D., Parikshak N.N., Gonatopoulos-Pournatzis T., Babor M., Quesnel-Vallières M., Tapial J., Raj B., O’Hanlon D., Barrios-Rodiles M., Sternberg M.J., Cordes S.P., Roth F.P., Wrana J.L., Geschwind D.H., Blencowe B.J. A highly conserved program of neuronal microexons is misregulated in autistic brains. Cell 2014 Dec 18; 159, 1511-1523 PubMed

Wegiel J., Flory M., Kuchna I., Nowicki K., Ma S.Y., Imaki H., Wegiel J., Cohen I.L., London E., Wisniewski T., Brown W.T. Stereological study of the neuronal number and volume of 38 brain subdivisions of subjects diagnosed with autism reveals significant alterations restricted to the striatum, amygdala and cerebellum. Acta Neuropathol. Commun. 2014 Sep 18; 2,141 PubMed

Camacho J., Ejaz E., Ariza J., Noctor S.C., Martínez-Cerdeño V. RELN-expressing neuron density in layer I of the superior temporal lobe is similar in human brains with autism and in age-matched controls. Neurosci. Lett. 2014 Sep 5; 579,163-167 PubMed

Nardone S., Sams D.S., Reuveni E., Getselter D., Oron O., Karpuj M., Elliott E. DNA methylation analysis of the autistic brain reveals multiple dysregulated biological pathways. Transl Psychiatry 2014 Sep 2; 4, e433 PubMed

Tang G., Gudsnuk K., Kuo S.H., Cotrina M.L., Rosoklija G., Sosunov A., Sonders M.S., Kanter E., Castagna C., Yamamoto A., Yue Z., Arancio O., Peterson B.S., Champagne F., Dwork A.J., Goldman J., Sulzer D. Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits. Neuron 2014 Sep 3; 83, 1131-1143 PubMed

Uppal N., Wicinski B., Buxbaum J.D., Heinsen H., Schmitz C., Hof P.R. Neuropathology of the anterior midcingulate cortex in young children with autism. J. Neuropathol. Exp. Neurol. 2014 Sep 1; 73, 891-902 PubMed 

Smith R.M., Banks W., Hansen E., Sadee W., Herman G.E. Family-based clinical associations and functional characterization of the serotonin 2A receptor gene (HTR2A) in autism spectrum disorder. Autism Res. 2014 Aug 1; 7, 459-4567 PubMed

Fatemi S.H., Reutiman T.J., Folsom T.D., Rustan O.G., Rooney R.J., Thuras P.D. Downregulation of GABAA receptor protein subunits α6, β2, δ, ε, γ2, θ, and ρ2 in superior frontal cortex of subjects with autism. J. Autism Dev. Disord. 2014 Aug 1; 44, 1833-1845 PubMed

Ben-David E., Shohat S., Shifman S. Allelic expression analysis in the brain suggests a role for heterogeneous insults affecting epigenetic processes in autism spectrum disorders. Hum. Mol. Genet. 2014 Aug 1; 23, 4111-4124. PubMed

Wegiel J., Flory M., Kuchna I., Nowicki K., Ma S.Y., Imaki H., Wegiel J., Cohen I.L., London E., Brown W.T., Wisniewski T. Brain-region-specific alterations of the trajectories of neuronal volume growth throughout the lifespan in autism. Acta Neuropathol. Commun. 2014 Mar 10; 2, 28 PubMed 

Stoner R., Chow M.L., Boyle M.P., Sunkin S.M., Mouton P.R., Roy S., Wynshaw-Boris A., Colamarino S.A., Lein E.S., Courchesne E. Patches of disorganization in the neocortex of children with autism. N. Engl. J. Med. 2014 Mar 27; 370, 1209-1219 PubMed

Uppal N., Gianatiempo I., Wicinski B., Schmeidler J., Heinsen H., Schmitz C., Buxbaum J.D., Hof P.R. Neuropathology of the posteroinferior occipitotemporal gyrus in children with autism. Mol. Autism 2014 Feb 24; 5, 17 PubMed  

Zhubi A., Chen Y., Dong E., Cook E.H., Guidotti A., Grayson D.R. Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum. Transl. Psychiatry 2014 Jan 21; 4, e349 PubMed

Edmonson C., Ziats M.N., Rennert O.M. Altered glial marker expression in autistic post-mortem prefrontal cortex and cerebellum. Mol. Autism 2014 Jan 10; 5, 3 PubMed

2013 Publications

Zhu L., Wang X., Li X.L., Towers A., Cao X., Wang P., Bowman R., Yang H., Goldstein J., Li Y.J., Jiang Y.H. Epigenetic dysregulation of SHANK3 in brain tissues from individuals with autism spectrum disorders. Hum. Mol. Genet. 2014 Mar 15; 23, 1563-1578 PubMed

Casanova M.F., El-Baz A.S., Kamat S.S., Dombroski B.A., Khalifa F., Elnakib A., Soliman A., Allison-McNutt A., Switala A.E. Focal cortical dysplasias in autism spectrum disorders. Acta Neuropathol. Commun. 2013 Oct 11; 1, 67 PubMed 

Eran A., Li J.B., Vatalaro K., McCarthy J., Rahimov F., Collins C., Markianos K., Margulies D.M., Brown E.N., Calvo S.E., Kohane I.S., Kunkel L.M. Comparative RNA editing in autistic and neurotypical cerebella. Mol. Psychiatry 2013 Sep 1; 18, 1041-1048 PubMed

Oblak A., Gibbs T.T., Blatt G.J. Reduced serotonin receptor subtypes in a limbic and a neocortical region in autism. Autism Res. 2013 Dec 1; 6, 571-583 PubMed 

Fatemi S.H., Folsom T.D., Kneeland R.E., Yousefi M.K., Liesch S.B., Thuras P.D. Impairment of fragile X mental retardation protein-metabotropic glutamate receptor 5 signaling and its downstream cognates ras-related C3 botulinum toxin substrate 1, amyloid beta A4 precursor protein, striatal-enriched protein tyrosine phosphatase, and homer 1, in autism: A postmortem study in cerebellar vermis and superior frontal cortex. Mol. Autism 2013 Jun 26; 4, 21 PubMed 

Tang G., Gutierrez Rios P., Kuo S.H., Akman H.O., Rosoklija G., Tanji K., Dwork A., Schon E.A., Dimauro S., Goldman J., Sulzer D. Mitochondrial abnormalities in temporal lobe of autistic brain. Neurobiol. Dis. 2013 Jun 1; 54, 349-361 PubMed 

Lahiri D.K., Sokol D.K., Erickson C., Ray B., Ho C.Y., Maloney B. Autism as early neurodevelopmental disorder: Evidence for an sAPPα-mediated anabolic pathway. Front. Cell Neurosci. 2013 Jun 21; 7, 94 PubMed 

Vardarajan B.N., Eran A., Jung J.Y., Kunkel L.M., Wall D.P. Haplotype structure enables prioritization of common markers and candidate genes in autism spectrum disorder. Transl. Psychiatry 2013 May 28; 3, e262 PubMed 

Sarachana T., Hu V.W. Genome-wide identification of transcriptional targets of RORA reveals direct regulation of multiple genes associated with autism spectrum disorder. Mol. Autism 2013 May 22; 4, 14 PubMed 

Jacot-Descombes S., Uppal N., Wicinski B., Santos M., Schmeidler J., Giannakopoulos P., Heinsen H., Schmitz C., Hof P.R. Decreased pyramidal neuron size in Brodmann areas 44 and 45 in patients with autism. Acta Neuropathol. 2012 Jul 1; 124, 67-79 PubMed 

Wegiel J., Frackowiak J., Mazur-Kolecka B., Schanen N.C., Cook E.H. Jr, Sigman M., Brown W.T., Kuchna I., Wegiel J., Nowicki K., Imaki H., Ma S.Y., Chauhan A., Chauhan V., Miller D.L., Mehta P.D., Flory M., Cohen I.L., London E., Reisberg B., de Leon M.J., Wisniewski T. Abnormal intracellular accumulation and extracellular Aβ deposition in idiopathic and Dup15q11.2-q13 autism spectrum disorders. PLoS One 2012 Jan 1; 7, e35414 PubMed 

Wegiel J., Schanen N.C., Cook E.H., Sigman M., Brown W.T., Kuchna I., Nowicki K., Wegiel J., Imaki H., Ma S.Y., Marchi E., Wierzba-Bobrowicz T., Chauhan A., Chauhan V., Cohen I.L., London E., Flory M., Lach B., Wisniewski T. Differences between the pattern of developmental abnormalities in autism associated with duplications 15q11.2-q13 and idiopathic autism. J. Neuropathol. Exp. Neurol. 2012 May 1; 71, 382-397 PubMed 

Wegiel J., Kuchna I., Nowicki K., Imaki H., Wegiel J., Ma S.Y., Azmitia E.C., Banerjee P., Flory M., Cohen I.L., London E., Brown W.T., Komich Hare C., Wisniewski T. Contribution of olivofloccular circuitry developmental defects to atypical gaze in autism. Brain Res. 2013 May 28; 1512, 106-122 PubMed 

Chung K., Wallace J., Kim S.Y., Kalyanasundaram S., Andalman A.S., Davidson T.J., Mirzabekov J.J., Zalocusky K.A., Mattis J., Denisin A.K., Pak S., Bernstein H., Ramakrishnan C., Grosenick L., Gradinaru V., Deisseroth K. Structural and molecular interrogation of intact biological systems. Nature 2013 May 16; 497, 332-337 PubMed

Kerin T., Ramanathan A., Rivas K., Grepo N., Coetzee G.A., Campbell D.B. A noncoding RNA antisense to moesin at 5p14.1 in autism. Sci. Transl. Med. 2012 Apr 4; 4, 128ra40 PubMed 

Morgan J.T., Chana G., Abramson I., Semendeferi K., Courchesne E., Everall I.P. Abnormal microglial-neuronal spatial organization in the dorsolateral prefrontal cortex in autism. Brain Res. 2012 May 25; 1456, 72-81 PubMed 

Ginsberg M.R., Rubin R.A, Natowicz M.R. Patterning of regional gene expression in autism: New complexity. Sci. Rep. 2013 Jan 1; 3,1831 PubMed

Shimmura C., Suzuki K., Iwata Y., Tsuchiya K.J., Ohno K., Matsuzaki H., Iwata K., Kameno Y., Takahashi T., Wakuda T., Nakamura K., Hashimoto K., Mori N. Enzymes in the glutamate-glutamine cycle in the anterior cingulate cortex in postmortem brain of subjects with autism. Mol. Autism 2013 Mar 26; 4, 6 PubMed 

Muratore C.R., Hodgson N.W., Trivedi M.S., Abdolmaleky H.M., Persico A.M., Lintas C., De la Monte S., Deth R.C. Age-dependent decrease and alternative splicing of methionine synthase mRNA in human cerebral cortex and an accelerated decrease in autism. PLoS One 2013 Jan 1; 8, e56927 PubMed 

Pearson B.L., Corley M.J., Vasconcellos A., Blanchard D.C., Blanchard R.J. Heparan sulfate deficiency in autistic postmortem brain tissue from the subventricular zone of the lateral ventricles. Behav. Brain Res. 2013 Apr 15; 243, 138-145 PubMed

Ginsberg M.R., Rubin R.A., Natowicz M.R. Patterning of regional gene expression in autism: New complexity. Sci. Rep. 2013 Jan 1; 3, 1831 PubMed 

2012 Publications

Ginsberg M.R., Rubin R.A., Falcone T., Ting A.H., Natowicz M.R. Brain transcriptional and epigenetic associations with autism. PLoS One 2012; 7, e44736 PubMed 

Garcia K.L., Yu G., Nicolini C., Michalski B., Garzon D.J., Chiu V.S., Tongiorgi E., Szatmari P., Fahnestock M. Altered balance of proteolytic isoforms of pro-brain-derived neurotrophic factor in autism. J. Neuropathol. Exp. Neurol. 2012 Apr 1; 71, 289-297 PubMed

Chow M.L., Pramparo T., Winn M.E., Barnes C.C., Li H.R., Weiss L., Fan J.B., Murray S., April C., Belinson H., Fu X.D., Wynshaw-Boris A., Schork N.J., Courchesne E. Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages. PLoS Genet. 2012 Jan 1; 8, e1002592 PubMed 

Shulha H.P., Cheung I., Whittle C., Wang J., Virgil D., Lin C.L., Guo Y., Lessard A., Akbarian S., Weng Z. Epigenetic signatures of autism: Trimethylated H3K4 landscapes in prefrontal neurons. Arch. Gen. Psychiatry 2012 Mar 1; 69, 314-324 PubMed 

Weidenheim K.M., Escobar A., Rapin I. Brief report: Life history and neuropathology of a gifted man with Asperger syndrome. J. Autism Dev. Disord. 2012 Mar 1; 42, 460-467 PubMed 

Mukaetova-Ladinska E.B., Perry E., Baron M., Povey C. Autism Ageing Writing Group. Ageing in people with autistic spectrum disorder. Int .J. Geriatr. Psychiatry 2012 Feb 1; 27, 109-118 PubMed